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Index > Protein center > Fgf23(Gene name) > Rat
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  • Fgf23 (Gene name),
  • Fibroblast growth factor 23 (Protein name ),  FGF23_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Fgf23;
    Protein name:
    Fibroblast growth factor 23(FGF-23);
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL and heparan sulfate glycosaminoglycans that function as coreceptors.
    Function:
    Regulator of phosphate homeostasis (By similarity). Inhibits renal tubular phosphate transport by reducing SLC34A1 levels (By similarity). Regulator of vitamin-D metabolism (By similarity). Negatively regulates osteoblasts differentiation and matrix mineralization (By similarity). Acts directly on the parathyroid to decrease PTH secretion. Upregulates EGR1 expression in the presence of KL.
    Subcellular Location:
    Secreted Secretion is dependent on O-glycosylation.
    Protein Attributes:
    Sequence length:
    251
    Sequence:
    50:
    MLGACLRLLV | GALCTVCSLG | TARAYSDTSP | LLGSNWGSLT | HLYTATARNS | 
    100:
    YHLQIHRDGH | VDGTPHQTIY | SALMITSEDA | GSVVIIGAMT | RRFLCMDLRG | 
    150:
    NIFGSYHFSP | ENCRFRQWTL | ENGYDVYLSP | KHHYLVSLGR | SKRIFQPGTN | 
    200:
    PPPFSQFLAR | RNEVPLLHFY | TARPRRHTRS | AEDPPERDPL | NVLKPRPRAT | 
    250:
    PIPVSCSREL | PSAEEGGPAA | SDPLGVLRRG | RGDARRGAGG | TDRCRPFPRF | 
    251:
    V
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat FGF-23
    Cat.:
    E0746m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat FGF-23
    Cat.:
    E0746h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat FGF-23
    Cat.:
    E0746r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat FGF-23
    Cat.:
    U0746h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat FGF-23
    Cat.:
    U0746m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat FGF-23
    Cat.:
    U0746r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat FGF-23
    Cat.:
    P0746Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat FGF-23
    Cat.:
    P0746Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat FGF-23
    Cat.:
    P0746Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat FGF-23
    Monoclonal Antibody for Rat FGF-23
    Monoclonal Antibody for Rat FGF-23
    Protein for Rat FGF-23
    Protein for Rat FGF-23
    Protein for Rat FGF-23

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    References
    1. 1.
      "Rattus norvegicus fgf23."
      Itoh N.
      Submitted (2002-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Klotho converts canonical FGF receptor into a specific receptor for FGF23."
      Urakawa I. , Yamazaki Y. , Shimada T. , Iijima K. , Hasegawa H. , Okawa K. , Fujita T. , Fukumoto S. , Yamashita T.
      Nature444:770-774(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
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